Cephalalgia is the premier international journal dedicated to advancing knowledge and clinical practice in headache and facial pain, published monthly on behalf of the International Headache Society (IHS).

The journal provides a global platform for high-impact research that drives innovation in diagnosis, treatment, and understanding of primary and secondary headache disorders and facial pain. Through a rigorous selection of papers for publication, Cephalalgia delivers trusted, cutting-edge insights that elevate the standards of headache and facial pain medicine worldwide.

The scope of Cephalalgia spans both clinical and translational research, encompassing the following key topics within headache and facial pain:

– Guidelines, Position and Scientific Statements: Evidence-based guidelines, clinical practice recommendations, position statements, and scientific documents developed by the International Headache Society, either independently or in collaboration with other stakeholders.

– Epidemiology and Burden: Studies on prevalence, impact, and healthcare implications of headache disorders. For submission of Global Burden of Disease (GBD) studies, authors should be GBD collaborators.

– Genetics and Epigenetics: Genetic insights and epigenetic factors influencing headache susceptibility and severity.

– Neurophysiology: Techniques and findings in imaging and electrophysiological research relevant to headaches.

– Biomarkers: Identification and validation of biomarkers for diagnosis, prognosis, and treatment response.

– Pathophysiology and Mechanisms: Insights into the biological and neural processes underlying headache disorders.

– Diagnosis and Management: Innovative approaches to improve patient care and outcomes, including studies aimed to validate or evolve the headache classification.

– Pharmacology and Treatment: Advancements in pharmacological and non-pharmacological interventions.

– Emerging Trends and Groundbreaking Findings: Results of scientific studies and new ideas that could pave the way for more targeted research in headache medicine.

– Real-word evidence: Findings form multicentric, multinational large scale studies to advance the knowledge of headache and facial pain.

– Headache Classification: Studies that add important new insights to better classify headache disorders or large collaborative multicenter studies validating the latest classification criteria for headache disorders.

– e-Health and Artificial Intelligence: Digital health innovations and AI applications in understanding headache pathophysiology, diagnosis and management.

– Medico-Legal Aspects: Exploration of legal considerations in the diagnosis and treatment of headache disorders.

– Pharmacoeconomics: Economic evaluations of headache treatments and their implications for healthcare policies.

To submit your manuscript online, please click here.

All articles will undergo a rapid and rigorous peer review process; once accepted, they will be promptly published online within days and made freely accessible under an Open Access model.

For submission inquiries or questions about manuscript suitability, please contact our Managing Editor, Wendy Krank: editorial.cephalalgia@gmail.com.

As a member of the Committee on Publication Ethics (COPE). Cephalalgia upholds the highest standards of integrity and transparency, supporting the advancement of ethical research in headache medicine.